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| Description: |
An addictive stimulant that is closely related to amphetamine but has a longer lasting and more toxic effect on the central nervous system. It has a high potential for abuse and addiction. |
| Street Names: |
Speed, meth, crystal meth, ice, glass, tina, beanies, clear,
cris, cristina, crypto, fast, rock, sketch, spoosh (for a
full listing, go to www.whitehousedrugpolicy.gov/streetterms/default.asp) |
| General Effects: |
Increased wakefulness and physical activity, decreased appetite. Long term use can lead to psychotic behavior, hallucination and stroke. |
| Use Trends: |
Nearly 12 million Americans have tried methamphetamine according
to the 2004 National Survey on Drug Use and Health. |
Methamphetamine, also referred to as crystal methamphetamine,
is a white, odorless, bitter tasting crystalline powder that acts
as a powerfully addictive stimulant dramatically affecting many
areas of the central nervous system. The immediate “high”,
or expected and desired meth side effects (or symptoms of meth
use) include euphoria, increased energy and attentiveness, diarrhea,
nausea, excessive sweating, loss of appetite, insomnia, jaw clenching,
tremors, agitation, compulsive fascination with repetitive tasks,
talkativeness, irritability, panic, increased libido or sexual
desire and dilated pupils. Health conditions associated with meth
abuse include memory loss, aggression, violence, psychotic behavior,
heart damage, neurological damage, weight loss, rapid tooth decay
(“meth mouth”), meningitis, paranoia, delusions, hallucinations,
severe headaches, skin sensations, compulsive picking, skin infections,
muscle tissue breakdown, kidney failure and increased occurrence
of communicable diseases such as HIV, AIDS and hepatitis. Street
names for methamphetamine include: meth, crystal meth, speed,
chalk, ice, crystal, crank and glass. Different street names are
used depending on how methamphetamine is used or taken. It can
be taken swallowed, snorted, smoked, injected (with or without
being dissolved in water), as well as inserted anally and into
the urethra. Between 1994 and 2002, the country experienced a
113% (more than double) increase in emergency room visits associated
with methamphetamine and similar stimulants. While originally
primarily used on the West Coast (San Diego has long been considered
the crystal meth capital), meth labs began appearing all over
the country and its use is now widespread. To date there are no
pharmacologic agents developed or proven to be effective in treating
crystal meth addiction and current treatment methods available
to the meth addict consist largely of behavioral interventions
and have been disappointing.
WHAT IS METH: How is it different from other stimulants
like cocaine?
Methamphetamine is a very addictive stimulant drug that activates
certain systems in the brain. It is a Schedule II stimulant, which
means it has a high potential for abuse and is legally available
(under the brand name Desoxyn) by prescriptions which cannot be
refilled for the treatment of certain ADDH, sleep and eating disorders
that persist despite the use of other pharmacologic agents.
Meth differs from cocaine as follows:

METH HISTORY
Legally, methamphetamine use is considered a second-line of treatment
and uncommonly prescribed narcolepsy (sleeping fits) and obesity
under a brand name. It was first synthesized in Japan and was
commonly used by Adolf Hitler and German pilots and soldiers in
WW II. In the 1950’s meth use increased in the US. It was
legally prescribed for narcolepsy, some forms of Parkinson’s
disease, alcoholism, certain depressive states, and obesity. The
rise of recreational meth use, from meth manufactured in meth
labs for personal use and distribution, began peaking in the late
1980’s and continued to rise into the new millennium.
THE SPRAWL OF METH ACROSS THE US

In 1983 the US passed laws prohibiting possession
of precursors and equipment for methamphetamine production. Federal
and state governments continued passing laws to curb the manufacture
of crystal meth, including the Combat Methamphetamine Epidemic
Act of 2005. In 2006, the US Department of Justice declared November
30, 2006 as Methamphetamine Awareness Day, dedicated to increasing
the availability of meth information to the general public.
METH ADDICTS AND USERS
Traditionally meth use was associated with white,
male, blue-collar workers but is now reportedly being used by
diverse groups in all regions of the country. According to the
2005 National Survey on Drug Use and Health (NSDUH), an estimated
10.4 million people age 12 or older have tried methamphetamine
at some point in their lives. Approximately 1.3 million reported
using methamphetamine over the past year and 512,000 reported
using meth within the last month. The 2005 Monitoring the Future
(MTF) survey of study drug use and attitudes reported 4.5% of
high school seniors had used meth, 4.1% of 10th graders had used
meth and 3.1% of 8th graders (approximately 14 year olds!) had
use meth within their short lives. Admission to methamphetamine
treatment programs represented 8% of all admission to drug rehab
in 2004. In 1992, only 5 states reported high numbers of methamphetamine
addiction as the primary problem reported at treatment admission.
In 2002 more than a third of the country (21 states) reported
high numbers of methamphetamine abuse as the primary concern at
admission, a greater than 400% increase in 10 years.
Increased use is also reported among young adults
and associated with those who attend private clubs and ‘raves’
as well as homeless and runaway populations. Commercial sex workers,
motorcycle gang members and gay populations are all experiencing
an increase in the use of meth, potentially contributing to the
spread of sexually transmitted disease, HIV/AIDS and hepatitis.
Occupations that require long hours of alertness and physical
endurance, such as long haul trucking, have also seen a rise in
methamphetamine use.
METHAMPHETAMINE EFFECTS
The effects of methamphetamine are primarily related to is action
as a potent central nervous system stimulant affecting the body’s
mechanisms for regulating heart rate, body temperature, blood
pressure, apetite, attention, mood, alertness and alarm responses.
Meth can be taken in a number of ways: swallowed, snorted, smoked,
injected, anally and through the urethra. Methods which increase
the brain’s uptake of the substance have been increasing;
snorting is faster than swallowing, smoking is faster than snorting,
etc… The drug alters the mood in different ways, depending
on the route of administration. Immediately after smoking meth
or injecting it intravenously, the user experiences an intense
rush or “flash” that lasts only a few minutes and
is described as extremely pleasurable. Snorting or swallowing
meth resulting in euphoria, described as a high but not a rush.
While the effects of smoking and IV injection are instantaneous,
smoking meth produces effects within 3 to 5 minutes and oral injection
can take up to 20 minutes to produce a high.
The pleasurable effects of crystal meth disappear even before
the blood concentration of the drug falls significantly; in other
words, it just stops working. Thus, more meth and increasing frequency
of use are necessary to maintain the high. Users indulge in binge
behavior for days at a time; foregoing food, hygiene, sleep and
other necessities.
Recent research shows methamphetamine abuse and dependence to
be associated with long lasting alterations in brain electrical
activity and function. These changes in the brain are similar
to those seen in people with degenerative brain diseases. It is
believed that methamphetamine use actually ‘trims’
the nerve cells in the brain, rendering the pathways incapable
of communication and resulting in the state of anhedonia or the
inability to experience pleasure.
| SHORT TERM EFFECTS
MAY INCLUDE:
- Increased attention
- Decreased fatigue
- Increased activity
- Increased wakefulness
- Decreased appetite
- Euphoria
- Euphoric rush or “flash”
- Increased respiration
- Rapid and Irregular heart beat
- Increased body temperature
- Diarrhea, nausea
- Jaw clenching and tremors
- Increases sexual desire
- Sexual preoccupation and urgency
- Inability to climax sexually
- Dialated pupils
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LONG TERM EFFECTS
MAY INCLUDE:
- Addiction
- Psychosis
- Paranoia
- Hallucinations
- Delusions
- Compulsive repetition of simple tasks
- Uncontrolled repetition of motor activity
- Changes in brain structure and function
- Memory loss
- Aggressive or Violent behavior
- Mood disturbances
- Severe dental problems
- Extreme weight loss
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In addition, side effect associated with meth
overdose include brain damage, meningitis, neurotoxicity, sensations
of flesh crawling with bugs, compulsive picking and infecting
sores, severe headache, muscle breakdown and kidney failure. There
are currently no medications available to treat methamphetamine
overdose.
METH REHAB AND TREATMENT
The most effective means for dramatically impacting
meth use is prevention strategies aimed at local communities.
In general, prevention program should start early, be comprehensive
and repetitive. Family-focused prevention efforts have been found
to have a greater impact than strategies that focus on parents
or children/adolescents only.
Withdrawal from methamphetamine is typically
characterized by intense drug cravings, depression, insomnia,
and increased appetite.
Several cognitive behavioral interventions designed
to help modify the patient’s thinking and behaviors, and
to increase coping skills related to various life stressors are
considered promising when conducted long term. Due to the degenerative
effects on the brain, and the slow readjustment and compensation
efforts of the brain following cessation of use, most short term
treatment strategies have yielded little if any results.
There are no medications available to treat addiction
or overdose to methamphetamine.
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